Review paper
Complement – known and unknown facts
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Publication date: 2011-06-20
Cent Eur J Immunol 2011;36(2):108-112
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ABSTRACT
This paper presents the selected issues regarding the functioning of the complement system, namely its activation pathways and regulating mechanisms. It explains its role in innate immunity, as well as in adaptive immunity. This study gives examples of diseases associated with the dysfunctions of the complement system, and characterizes some mechanisms of pathogens that may inhibit complement activity.