Among rabbit haemorrhagic disease virus (RHDV) strains, there are some of them, nominated as antigenic variants, which have not been studied to the extent of haematological parameters. Moreover, antigenic variants differ in haemagglutination capacity. The paper aim at examining the dynamic changes in the values of white and red blood cells indexes in four haemagglutinating (Vt97 and Hartmannsdorf) and non-haemagglutinating (Pv97 and 9905) antigenic variants of RHDV. The study indeed showed differences among examined strains that were not depending on haemagglutination property.