The in vivo effect of two composed herbal remedies Echinasal and Bioaron C on specific cellular and humoral immunity in mice was studied. Stimulatory effect on the local graft-versus-host reaction (immunological angiogenesis) was presented by feeding donor mice for 7 days with both remedies. Angiogenic activity of maternal donor spleen lymphocytes was more efficiently stimulated by Bioaron C than by Echinasal. Stimulatory effect on anti-SRBC antibody production was presented by feeding mice for 7 days before immunization with 40 or 80 µl daily dose of Echinasal (p < 0.01 and p < 0.001, respectively), and 30 µl daily dose of Bioaron C (p < 0.01). Higher (90 µl) daily dose of Bioaron C presented stimulation on the border of statistical significance (p < 0.1).