Pulsed electromagnetic fields (PEMF) have been shown to be clinically beneficial, effective for bone and wound repair, but their mechanism of action is not fully elucidated. Angiogenesis plays an important role in injured tissue healing and during the wound repair many potential angiogenic factors are released. It was reported that PEMF may increase angiogenesis through endothelial release of basic fibroblast growth factor (bFGF). Moreover, an increase of protein synthesis by cells exposed to a 1,800-MHz radiofrequency mobile phone PEMF was detected by proteome profiling. We previously reported that immune activity of lymphocytes and monocytes in culture can be intensified by 900 MHz microwaves. In the present study, we performed experiments with murine endothelial cell line HECa10, exposed to the influence of pulse modulated 900 MHz microwave electromagnetic field. Fifteen minutes exposure resulted in significant stimulation of endothelial cells proliferation rate, what we evaluated by two independent methods (Alamar Blue reduction and 3H thymidine incorporation).