CLINICAL IMMUNOLOGY
The effect of hydrolysates of proteins from rice milk on the physiological response
of enterocytes and on the adhesion of bacteria from healthy and allergic people –
an in vitro study
Submission date: 2015-12-16
Final revision date: 2016-04-01
Acceptance date: 2016-04-04
Publication date: 2017-01-24
Cent Eur J Immunol 2016;41(4):363-375
KEYWORDS
rice milkmilk substituteallergy to cow’s milkintestinal bacteriabacterial adhesionintestinal ecosystem
ABSTRACT
Designing an optimal diet requires knowledge of the biological activity of food products, particularly in relation to people with food allergies. The hypothesis, which constitutes the basis of this thesis, states that the peptides and glycopeptides released from proteins by enzymatic hydrolysis are able to change the quantity and quality of the human gastrointestinal ecosystem. Such substrates may interfere with adhesion to the intestinal epithelium microbiota and alter enterocytic metabolic activity. The aim of this study was to determine the effect of protein hydrolysates from rice milk substitute on gut epithelial cells and the intestinal microbiota of healthy people and ones suffering from an allergy to milk. The following experimental work applied systems that reflect the conditions occurring in the gastrointestinal tract.
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