Diagnostic and therapeutic difficulties in hypogammaglobulinemia in adults

Patients with rheumatic diseases have various abnormalities in immune system. One of these is hypogammaglobulinemia, that can be caused by different factors (medicines, genetic defects, infectious diseases, secondary immune deficiencies, neoplasms). Patients with primary immunodeficiency have higher incidence of autoimmune diseases. We report on clinical cases of hypogammaglobulinemia as a result of treatment with gold salts and hypogammaglobulinemia in a patient with spondyloarthropathy.

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Clinical immunology
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eISSN:	1644-4124
ISSN:	1426-3912