DNA and RNA oligonucleotides as a new class of drugs
Publication date: 2009-12-30
Cent Eur J Immunol 2009;34(4):280-283
KEYWORDS
ABSTRACT
Aptamers are short synthetic single-stranded DNA or RNA oligonucleotides forming unique 3-D conformation. They are able to bind and neutralize their target molecules with high specificity and affinity. Therefore, they may specifically interfere in vivo with some protein function and thus display drug-like properties. This paper provides a brief description of possible clinical application of aptamers arguing for their tremendous therapeutic possibilities.
| eISSN: | 1644-4124 |
| ISSN: | 1426-3912 |
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