Clinical immunology
Periodontal disease and cytokine inhibitors
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Publication date: 2006-10-12
Cent Eur J Immunol 2006;31(1-2):1-2
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ABSTRACT
The aim of the presented paper was to examine the occurrence in saliva of interleukin – 1 receptor antagonist (IL-1 ra) and soluble receptor type I of tumor necrosis factor (sTNF RI) in patients with periodontitis. The levels of interleukin-1 receptor antagonist and soluble TNF receptor type I (s TNF RI, p55) in saliva were determined with an immunoenzymatic ELISA method using a factory-ready quantitative enzymatic test manufactured by Quantikine, R&D System. The level of occurrence for interleukin-1 receptor antagonist (IL-1 ra) in saliva was statistically significantly higher (p<0.05) in persons with periodontitis as compared with the control group.