Clinical immunology
Laboratory diagnosis of autoimmune hepatitis
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Publication date: 2010-04-06
Cent Eur J Immunol 2010;35(1):37-40
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ABSTRACT
Autoimmune liver diseases include autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and primary sclerosing cholangitis (PSC). There is no specific diagnostic test for autoimmune hepatic diseases. Diagnosis is based on careful exclusion of other causes of chronic liver disease like viral, metabolic, genetic and toxic aetiologies of chronic hepatitis or hepatic injury, together with the finding of several suggestive laboratory markers. The paper describes major autoantibodies and serological diagnostic strategies in patients with autoimmune hepatitis.