1. Tossetta G, Fantone S, Gesuita R, et al. (2022): HtrA1 in gestational diabetes mellitus: A possible biomarker? Diagnostics 12: 2705.
2.
Perugini J, Di Mercurio E, Tossetta G, et al. (2019): Biological effects of ciliary neurotrophic factor on hMADS adipocytes. Front Endocrinol 10: 768.
3.
Tossetta G, Piani F, Borghi C, Marzioni D (2023): Role of CD93 in health and disease. Cells 12: 1778.
4.
Piani F, Tossetta G, Cara-Fuentes G, et al. (2023): Diagnostic and prognostic role of CD93 in cardiovascular disease: a systematic review. Biomolecules 13: 910.
5.
Roncarolo MG, Battaglia M (2007): Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. Nat Rev Immunol 7: 585-598.
6.
Deshmukh H, Way SS (2019): Immunological basis for recurrent fetal loss and pregnancy complications. Annu Rev Pathol 14: 185-210.
7.
Chen J, Zhao L, Wang D, et al. (2019): Contribution of regulatory T cells to immune tolerance and association of microRNA 210 and Foxp3 in preeclampsia. Mol Med Rep 19: 1150-1158.
8.
Corthay A (2009): How do regulatory T cells work? Scand J Immunol 70: 326-336.
9.
Vignali DA, Collison LW, Workman CJ (2008): How regulatory T cells work. Nat Rev Immunol 8: 523-532.
10.
Hosseini S, Shokri F, Pour SA, et al. (2016): A shift in the balance of T17 and Treg cells in menstrual blood of women with unexplained recurrent spontaneous abortion. J Reprod Immunol 116: 13-22.
11.
Field EH, Kulhankova K, Nasr ME (2007): Natural Tregs, CD4+ CD25+ inhibitory hybridomas, and their cell contact dependent suppression. Immunol Res 39: 62-78.
12.
Huang N, Chi H, Qiao J (2020): Role of regulatory T cells in regulating fetal-maternal immune tolerance in healthy pregnancies and reproductive diseases. Front Immunol 11: 1023.
13.
Veldhoen M, Hocking RJ, Atkins CJ, et al. (2006): TGF in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24: 179-189.
14.
Konkel JE, Zhang D, Zanvit P, et al. (2017): Transforming growth factor- signaling in regulatory T cells controls T helper-17 cells and tissue-specific immune responses. Immunity 46: 660-674.
15.
Fujimoto Y, Kuramoto N, Yoneyama M, Azuma YT (2021): Interleukin-19 as an immunoregulatory cytokine. Curr Mol Pharmacol 14: 191-199.
16.
Liu YS, Wu L, Tong XH, et al. (2011): Study on the relationship between Th17 cells and unexplained recurrent spontaneous abortion. Am J Reprod Immunol 65: 503-511.
17.
Aluvihare VR, Betz AG (2006): The role of regulatory T cells in materno-fetal tolerance. Immunology of Pregnancy. Springer; 171-178.
18.
Guerin LR, Prins JR, Robertson SA (2009): Regulatory T-cells and immune tolerance in pregnancy: a new target for infertility treatment? Hum Reprod Update 15: 517-535.
19.
Bettelli E, Carrier Y, Gao W, et al. (2006): Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441: 235-238.
20.
Yang H, Qiu L, Chen G, et al. (2008): Proportional change of CD4+ CD25+ regulatory T cells in decidua and peripheral blood in unexplained recurrent spontaneous abortion patients. Fertil Steril 89: 656-661.
21.
Somerset DA, Zheng Y, Kilby MD, et al. (2004): Normal human pregnancy is associated with an elevation in the immune suppressive CD25+ CD4+ regulatory T-cell subset. Immunology 112: 38-43.
22.
Wang WJ, Hao CF, Yin GJ, et al. (2010): Increased prevalence of T helper 17 (Th17) cells in peripheral blood and decidua in unexplained recurrent spontaneous abortion patients. J Reprod Immunol 84: 164-170.
23.
Lee S, Kim J, Hur S, et al. (2011): An imbalance in interleukin-17-producing T and Foxp3+ regulatory T cells in women with idiopathic recurrent pregnancy loss. Hum Reprod 26: 2964-2971.
24.
Wang WJ, Hao CF, Qu QL, et al. (2010): The deregulation of regulatory T cells on interleukin-17-producing T helper cells in patients with unexplained early recurrent miscarriage. Hum Reprod 25: 2591-2596.
25.
Sasaki Y, Sakai M, Miyazaki S, et al. (2004): Decidual and peripheral blood CD4+ CD25+ regulatory T cells in early pregnancy subjects and spontaneous abortion cases. Mol Hum Reprod 10: 347-353.
26.
Mei S, Tan J, Chen H, et al. (2010): Changes of CD4+ CD25 high regulatory T cells and FOXP3 expression in unexplained recurrent spontaneous abortion patients. Fertil Steril 94: 2244-2247.
27.
Wu L, Luo LH, Zhang YX, et al. (2014): Alteration of Th17 and Treg cells in patients with unexplained recurrent spontaneous abortion before and after lymphocyte immunization therapy. Reprod Biol Endocrinol 12: 74.
28.
Nakashima A, Ito M, Shima T, et al. (2010): Accumulation of IL-17-positive cells in decidua of inevitable abortion cases. Am J Reprod Immunol 64: 4-11.
29.
Sifnaios E, Mastorakos G, Psarra K, et al. (2019): Gestational diabetes and T-cell (Th1/Th2/Th17/Treg) immune profile. In vivo 33: 31-40.
30.
Sheu A, Chan Y, Ferguson A, et al. (2018): A proinflammatory CD4+ T cell phenotype in gestational diabetes mellitus. Diabetologia 61: 1633-1643.
31.
Gupta SC, Patchva S, Aggarwal BB (2013): Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J 15: 195-218.
32.
Xu XY, Meng X, Li S, et al. (2018): Bioactivity, health benefits, and related molecular mechanisms of curcumin: Current progress, challenges, and perspectives. Nutrients 10: 1553.
33.
Gupta SC, Patchva S, Koh W, Aggarwal BB (2012): Discovery of curcumin, a component of golden spice, and its miraculous biological activities. Clin Exp Pharmacol Physiol 39: 283-299.
34.
Momtazi AA, Shahabipour F, Khatibi S, et al. (2016): Curcumin as a MicroRNA regulator in cancer: a review. Rev Physiol Biochem Pharmacol 171: 1-38.
35.
Momtazi AA, Derosa G, Maffioli P, et al. (2016): Role of microRNAs in the therapeutic effects of curcumin in non-cancer diseases. Mol Diagn Ther 20: 335-345.
36.
Hatcher H, Planalp R, Cho J, et al. (2008): Curcumin: from ancient medicine to current clinical trials. Cell Mol Life Sci 65: 1631-1652.
37.
Baliga MS, Joseph N, Venkataranganna MV, et al. (2012): Curcumin, an active component of turmeric in the prevention and treatment of ulcerative colitis: preclinical and clinical observations. Food Funct 3: 1109-1117.
38.
Sahebkar A, Mohammadi A (2019): Targeting the balance of T helper cell responses by curcumin in inflammatory and autoimmune states. Autoimmun Rev 18: 738-748.
39.
Abdollahi E, Momtazi AA, Johnston TP, Sahebkar A (2018): Therapeutic effects of curcumin in inflammatory and immune-mediated diseases: A nature-made jack-of-all-trades? J Cell Physiol 233: 830-848.
40.
Tossetta G, Fantone S, Busilacchi EM, et al. (2022): Modulation of matrix metalloproteases by ciliary neurotrophic factor in human placental development. Cell Tissue Res 390: 113-129.
41.
International Association of Diabetes and Pregnancy Study Groups Consensus Panel; Metzger BE, Gabbe SG, Persson B, et al. (2010): International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy. Diabetes Care 33: 676-682.
42.
Queiroz AA, Franca EL, Hara CC, et al. (2019): Phenotypic characterization of regulatory T cells populations in maternal blood, cord blood and placenta from diabetic mothers. J Matern Fetal Neonatal Med 32: 1098-1104.
43.
Sharma S, Banerjee S, Krueger PM, Blois SM (2022): Immunobiology of gestational diabetes mellitus in post-Medawar era. Front Immunol 12: 758267.
44.
Eghbal-Fard S, Yousefi M, Heydarlou H, et al. (2019): The imbalance of Th17/Treg axis involved in the pathogenesis of preeclampsia. J Cell Physiol 234: 5106-5116.
45.
Li N, Saghafi N, Ghaneifar Z, et al. (2021): Evaluation of the Effects of 1, 25VitD3 on Inflammatory Responses and IL-25 Expression. Front Genet 12: 779494.
46.
Abdollahi E, Rezaee SA, Saghafi N, et al. (2020): Evaluation of the effects of 1, 25 vitamin D3 on regulatory T cells and T helper 17 cells in vitamin D-deficient women with unexplained recurrent pregnancy loss. Curr Mol Pharmacol 13: 306-317.
47.
Farshchi M, Abdollahi E, Saghafi N, et al. (2022): Evaluation of Th17 and Treg cytokines in patients with unexplained recurrent pregnancy loss (URPL). J Clin Transl Res 8: 256-265.
48.
Denney JM, Nelson EL, Wadhwa PD, et al. (2011): Longitudinal modulation of immune system cytokine profile during pregnancy. Cytokine 53: 170-177.
49.
Brogin Moreli J, Cirino Ruocco AM, Vernini JM, et al. (2012): Interleukin 10 and tumor necrosis factor-alpha in pregnancy: aspects of interest in clinical obstetrics. ISRN Obstet Gynecol 2012: 230742.
50.
Bates M, Quenby S, Takakuwa K, et al. (2002): Aberrant cytokine production by peripheral blood mononuclear cells in recurrent pregnancy loss? Hum Reprod 17: 2439-2444.
51.
Hanlon AM, Jang S, Salgame P (2002): Signaling from cytokine receptors that affect Th1 responses. Front Biosci 7: d1247-d1254.
52.
Cao W, Wang X, Chen T, et al. (2018): Maternal lipids, BMI and IL 17/IL 35 imbalance in concurrent gestational diabetes mellitus and preeclampsia. Exp Ther Med 16: 427-435.
53.
Abdollahi E, Saghafi N, Rezaee SAR, et al. (2020): Evaluation of 1, 25 (OH) 2D3 effects on FOXP3, ROR-t, GITR, and CTLA-4 gene expression in PBMCs of vitamin D-deficient women with unexplained recurrent pregnancy loss. Iran Biomed J 24: 295-305.
54.
Mohammadi S, Abdollahi E, Nezamnia M, et al. (2021): Adoptive transfer of Tregs: A novel strategy for cell-based immunotherapy in spontaneous abortion: Lessons from experimental models. Int Immunopharmacol 90: 107195.
55.
Abdollahi E, Tavasolian F, Momtazi-Borojeni AA, et al. (2016): Protective role of R381Q (rs11209026) polymorphism in IL-23R gene in immune-mediated diseases: A comprehensive review. J Immunotoxicol 13: 286-300.
56.
Angelo AG, Neves CT, Lobo TF, et al. (2018): Monocyte profile in peripheral blood of gestational diabetes mellitus patients. Cytokine 107: 79-84.
57.
Abdollahi E, Rezaee SA, Saghafi N, et al. (2020): Evaluation of the effects of 1,25 vitamin D3 on regulatory T cells and T helper 17 cells in vitamin D-deficient women with unexplained recurrent pregnancy loss. Curr Mol Pharmacol 13: 306-317.
58.
Liu D, Cao T, Wang N, et al. (2016): IL-25 attenuates rheumatoid arthritis through suppression of Th17 immune responses in an IL-13-dependent manner. Sci Rep 6: 1-11.
59.
Plows JF, Stanley JL, Baker PN, et al. (2018): The pathophysiology of gestational diabetes mellitus. Int J Mol Sci 19: 3342.
60.
Amirian A, Mahani MB, Abdi F (2020): Role of interleukin-6 (IL-6) in predicting gestational diabetes mellitus. Obstet Gynecol Sci 63: 407-416.
61.
Yang Y, Liu L, Liu B, et al. (2018): Functional defects of regulatory T cell through interleukin 10 mediated mechanism in the induction of gestational diabetes mellitus. DNA Cell Biol 37: 278-285.
62.
Chuengsamarn S, Rattanamongkolgul S, Luechapudiporn R, et al. (2012): Curcumin extract for prevention of type 2 diabetes. Diabetes Care 35: 2121-2127.
63.
Ghaneifar Z, Yousefi Z, Tajik F, et al. (2020): The potential therapeutic effects of curcumin on pregnancy complications: Novel insights into reproductive medicine. IUBMB Life 72: 2572-2583.
64.
Kumagai A, Itakura A, Koya D, Kanasaki K (2018): AMP-activated protein (AMPK) in pathophysiology of pregnancy complications. Int J Mol Sci 19: 3076.
65.
Ishii T, Miyazawa M, Takanashi Y, et al. (2014): Genetically induced oxidative stress in mice causes thrombocytosis, splenomegaly and placental angiodysplasia that leads to recurrent abortion. Redox Biol 2: 679-685.
66.
Handono K, Pratama MZ, Endharti AT, Kalim H (2015): Treatment of low doses curcumin could modulate Th17/Treg balance specifically on CD4+ T cell cultures of systemic lupus erythematosus patients. Cent Eur J Immunol 40: 461-469.
67.
Atabaki M, Shariati-Sarabi Z, Tavakkol-Afshari J, Mohammadi M (2020): Significant immunomodulatory properties of curcumin in patients with osteoarthritis; a successful clinical trial in Iran. Int Immunopharmacol 85: 106607.
68.
Ahmadi M, Hajialilo M, Dolati S, et al. (2020): The effects of nanocurcumin on Treg cell responses and treatment of ankylosing spondylitis patients: A randomized, double-blind, placebo-controlled clinical trial. J Cell Biochem 121: 103-110.
69.
Wang J, Zhai X, Guo J, et al. (2019): Long non-coding RNA DQ786243 modulates the induction and function of CD4+ Treg cells through Foxp3-miR-146a-NF-B axis: Implications for alleviating oral lichen planus. Int Immunopharmacol 75: 105761.
70.
Abdollahi E, Saghafi N, Rezaee SAR, et al. (2020): Evaluation of 1, 25 (OH) 2D3 effects on FOXP3, ROR-t, GITR, and CTLA-4 gene expression in PBMCs of vitamin D-deficient women with unexplained recurrent pregnancy loss. Iran Biomed J 24: 295-305.
71.
Xiao QP, Zhong YB, Kang ZP, et al. (2022): Curcumin regulates the homeostasis of Th17/Treg and improves the composition of gut microbiota in type 2 diabetic mice with colitis. Phytother Res 36: 1708-1723.
